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protein origami

A free puzzle game — play it in your browser, no install. Fold a toy protein on a grid to its lowest energy: the HP lattice model as a smooth, single-file browser game.

by @kraewon7422 · kraewon7422/protein-origami on GitHubLANG HTMLHOSTED ON KRAEWON7422.GITHUB.IOUPDATED 24 Oct 2026

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Controls: Keys: Z undo · R reset · H hint · L levels · N next level · Esc close

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From the README

A small browser game about how proteins fold. Fold a toy amino-acid chain on a grid until it reaches its lowest energy. The rules are the HP lattice model: amber beads are water-fearing, blue rings are water-loving.

One HTML file, no dependencies, no build step. A Korean guide follows the English one below.

I'm learning bioinformatics, and looking at protein structures in PyMOL made me wonder how a chain of amino acids ends up in that shape at all. I thought a game that lets me fold one myself would be a fun way to find out.

Read the full README on GitHub →

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